p26: a cell surface antigen expressed selectively by hematopoietic cells.
نویسندگان
چکیده
A monoclonal antibody (MoAb) H5 (IgG2b) was obtained by fusion between SP2/0, mouse myeloma cell line and spleen cells from BC3Fl mice immunized with HEL, a erythroleukemia cell line. MoAb H5 precipitated a 26 kilodalton (KD) polypeptide in reduced condition. It reacted with platelets, monocytes, eosinophiles, 13% of lymphocytes, thymocytes and colony-forming unitsgranulocyte/monocyte (CFU-GM), but not with neutrophiles, red blood cells (RBC) and burstforming units-erythroid (BFU-E). It also stained T-lymphoid leukemia cell lines but not B cell lines. Thus this antigen was expressed selectively by both myeloid and lymphoid lineages.
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ورودعنوان ژورنال:
- Hiroshima journal of medical sciences
دوره 37 3 شماره
صفحات -
تاریخ انتشار 1988